SCHEMBL9535478

SCHEMBL9535478

C=CCN1CC(O)c2cc(S(N)(=O)=O)sc2S1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 0.49
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7515457 0.81 CA2 (0.47) CA2CA4
SCHEMBL9534530 0.79 CA2 (0.47) CA2CA4
SCHEMBL7509438 0.77 CA2 (0.45) CA2
SCHEMBL9058096 0.76 CA2 (0.47) CA2CA4
SCHEMBL7510237 0.74 CA2 (0.51) CA2CA4
SCHEMBL9535803 0.70 KDM4E (0.30)
SCHEMBL10513096 0.66 CA2 (1.00) CA2
SCHEMBL9535520 0.66 CA2 (0.51) CA2CA4
SCHEMBL12495268 0.65 CA2 (0.58) CA2CA4
SCHEMBL3311384 0.65 CA2 (0.58) CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0527801-A4 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS 1993-03-10 EP disclosed
EP-0527801-A1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS ALCON LABORATORIES, INC. (US) 1993-02-24 EP disclosed
WO-1991015486-A1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS ALCON LABORATORIES, INC. (US) 1991-10-17 WO disclosed