Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058096 | 0.85 | CA2 (0.47) | CA2CA4CA12CA1CA6 | |
| SCHEMBL9115594 | 0.84 | CA2 (0.32) | CA2CA4CA12CA1CA6 | |
| SCHEMBL7518760 | 0.82 | CA2 (0.58) | CA2CA4CA12CA1CA6 | |
| SCHEMBL7510619 | 0.82 | CA2 (0.58) | CA2CA4CA12CA1CA6 | |
| SCHEMBL7515912 | 0.81 | CA2 (0.49) | CA2CA4CA12CA1CA6 | |
| SCHEMBL7510985 | 0.81 | CA2 (0.49) | CA2CA4CA12CA1CA6 | |
| SCHEMBL7509438 | 0.80 | CA2 (0.45) | CA2CA12CA1CA7CA9 | |
| SCHEMBL9535478 | 0.79 | CA2 (0.49) | CA2CA4 | |
| SCHEMBL7506048 | 0.78 | CA2 (0.57) | CA2CA4CA12CA1CA6 | |
| SCHEMBL7509335 | 0.78 | CA2 (0.57) | CA2CA4CA12CA1CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527801-A4 | THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS | — | 1993-03-10 | — | — | EP | disclosed |
| EP-0527801-A1 | THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991015486-A1 | THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1991-10-17 | — | — | WO | disclosed |