Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539173 | 0.87 | SLC6A9 (0.49) | SLC6A9HRH1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9535014 | 0.87 | SLC6A9 (0.55) | SLC6A9HRH1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9635911 | 0.86 | SLC6A9 (0.68) | SLC6A9HRH1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9535297 | 0.86 | SLC6A9 (0.47) | SLC6A9HRH1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9535215 | 0.85 | SLC6A9 (0.48) | SLC6A9HRH1KDM4ELMNASMN1; SMN2 | |
| Oxalic Acid SCHEMBL9535422 | 0.85 | SLC6A9 (0.49) | SLC6A9HRH1KDM4ELMNASMN1; SMN2 | |
| Oxalic Acid SCHEMBL9535426 | 0.85 | SLC6A9 (0.49) | SLC6A9HRH1KDM4ELMNASMN1; SMN2 | |
| Fumaric Acid SCHEMBL10382780 | 0.84 | SLC6A9 (0.49) | SLC6A9HRH1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9535194 | 0.84 | SLC6A9 (0.49) | SLC6A9HRH1KDM4ELMNASMN1; SMN2 | |
| Oxalic Acid SCHEMBL9535399 | 0.82 | SLC6A9 (0.47) | SLC6A9HRH1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |
| EP-0282133-A2 | 1-alkyl substituted benzimidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-09-14 | — | — | EP | disclosed |