Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 4/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536318 | 0.88 | SLC6A9 (0.45) | SLC6A9LMNASMN1; SMN2KDM4ECCR3 | |
| SCHEMBL9535554 | 0.87 | SLC6A9 (0.52) | SLC6A9LMNASMN1; SMN2KDM4EHRH1 | |
| SCHEMBL9537927 | 0.86 | LMNA (0.55) | SLC6A9LMNASMN1; SMN2KDM4ECCR3 | |
| SCHEMBL9538036 | 0.85 | CCR3 (0.48) | SLC6A9LMNASMN1; SMN2KDM4ECCR3 | |
| SCHEMBL9539173 | 0.85 | SLC6A9 (0.49) | SLC6A9LMNASMN1; SMN2KDM4EHRH1 | |
| SCHEMBL9635884 | 0.85 | SLC6A9 (0.64) | SLC6A9LMNAMEN1TSHRKMT2A | |
| Oxalic Acid SCHEMBL9535426 | 0.83 | SLC6A9 (0.49) | SLC6A9LMNASMN1; SMN2KDM4EHRH1 | |
| Oxalic Acid SCHEMBL9535422 | 0.83 | SLC6A9 (0.49) | SLC6A9LMNASMN1; SMN2KDM4EHRH1 | |
| Oxalic Acid SCHEMBL9538798 | 0.83 | SLC6A9 (0.47) | SLC6A9LMNASMN1; SMN2KDM4EHRH1 | |
| Oxalic Acid SCHEMBL9538801 | 0.83 | SLC6A9 (0.47) | SLC6A9LMNASMN1; SMN2KDM4EHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |