Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311325 | 0.79 | ADORA1 (0.40) | NPSR1ALDH1A1HPGDADORA2AADORA1 | |
| SCHEMBL9312792 | 0.79 | TDP1 (0.41) | NPSR1ALDH1A1NPC1TP53HPGD | |
| SCHEMBL9310587 | 0.77 | FABP3 (0.43) | FABP4FABP5ALDH1A1HPGDTSHR | |
| SCHEMBL9311135 | 0.76 | PTGS2 (0.36) | ALDH1A1TP53HPGDTSHRSMN1; SMN2 | |
| SCHEMBL7202279 | 0.74 | MEN1 (0.46) | ALDH1A1TP53HPGDTSHRHSD17B10 | |
| SCHEMBL6024044 | 0.73 | NPSR1 (0.50) | NPSR1ALDH1A1NPC1TP53HPGD | |
| SCHEMBL23609610 | 0.72 | FABP4 (0.48) | FABP4FABP5NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5099112 | 0.72 | FABP4 (0.62) | FABP4FABP5NPSR1ALDH1A1KMT2A | |
| SCHEMBL29975104 | 0.71 | FABP4 (0.44) | FABP4FABP5NPSR1ALDH1A1NPC1 | |
| SCHEMBL23609290 | 0.71 | FABP4 (0.44) | FABP4FABP5NPSR1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |