Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 6/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538826 | 0.87 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9535645 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9538048 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9536061 | 0.78 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9534494 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9534839 | 0.68 | HSD17B10 (0.49) | KDM4EALDH1A1HPGDHSD17B10DYRK3 | |
| SCHEMBL9537071 | 0.67 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9535280 | 0.67 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9833924 | 0.66 | CKS1B (0.84) | KDM4EALDH1A1HPGDHSD17B10CKS1B | |
| SCHEMBL18499244 | 0.65 | KDM4E (0.74) | KDM4EALDH1A1HPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353902-B1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-05 | — | — | EP | disclosed |
| EP-0353902-A1 | Substituted phenyltriazolopyrimidine herbicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |