Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535816 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9535484 | 0.86 | DRD3 (0.59) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9538815 | 0.84 | KDM4E (0.42) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9534436 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9147720 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9685920 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9686875 | 0.75 | ALDH1A1 (0.73) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9685571 | 0.75 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9045127 | 0.75 | TOP1 (0.61) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9686810 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549857-A1 | Antibacterial quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550019-A2 | Novel quinolone carboxylic acid derivatives and processes for preparing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |