Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536018 | 0.78 | ALDH1A1 (0.54) | ALDH1A1VCAM1MAPTCYP1A2CYP2C9 | |
| SCHEMBL3015778 | 0.75 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP1A2ALOX15CYP2C9 | |
| SCHEMBL698847 | 0.72 | VCAM1 (0.66) | ALDH1A1VCAM1MAPTGRIA1GRIA2 | |
| SCHEMBL2082451 | 0.72 | HSD17B10 (0.47) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL17888574 | 0.72 | CYP11B1 (0.47) | ALDH1A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL1343668 | 0.71 | TSHR (0.60) | ALDH1A1VCAM1MAPTGRIA1GRIA2 | |
| SCHEMBL10398270 | 0.71 | VCAM1 (0.50) | ALDH1A1VCAM1MAPTGRIA1GRIA2 | |
| SCHEMBL14253687 | 0.70 | KDM1A (0.53) | ALDH1A1ALOX15TDP1MEN1KMT2A | |
| SCHEMBL16953629 | 0.70 | VCAM1 (0.46) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL3053373 | 0.69 | MAPK1 (0.47) | ALDH1A1VCAM1MAPTGRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |