Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 2/20 | 0.63 |
| ▸ | DHFR | P00374 | 11/20 | 0.58 |
| ▸ | TYMS | P04818 | 2/20 | 0.48 |
| ▸ | ATIC | P31939 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535831 | 0.94 | GART (0.72) | GARTDHFRTYMSATIC | |
| SCHEMBL9263780 | 0.90 | GART (0.67) | GARTDHFRTYMSATIC | |
| SCHEMBL9537018 | 0.86 | DHFR (0.59) | GARTDHFR | |
| SCHEMBL9535980 | 0.85 | GART (0.73) | GARTDHFR | |
| SCHEMBL9208538 | 0.85 | GART (0.60) | GARTDHFRTYMSATIC | |
| SCHEMBL9208525 | 0.85 | GART (0.60) | GARTDHFRTYMSATIC | |
| SCHEMBL9446052 | 0.84 | GART (0.59) | GARTDHFRTYMSATIC | |
| SCHEMBL9446084 | 0.82 | DHFR (0.69) | GARTDHFR | |
| SCHEMBL9538587 | 0.81 | DHFR (0.61) | GARTDHFRTYMSATIC | |
| SCHEMBL9052458 | 0.80 | GART (0.44) | GARTDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215063-B1 | PYRIDO (2,3-d )PYRIMIDIN DERIVATIVES | UNIV PRINCETON (US) | 1993-11-03 | — | — | EP | claimed |