Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 8/20 | 0.59 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.48 |
| ▸ | SLC19A1 | P41440 | 1/20 | 0.48 |
| ▸ | SLC46A1 | Q96NT5 | 1/20 | 0.48 |
| ▸ | GART | P22102 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494143 | 0.94 | DHFR (0.67) | DHFRFOLR1SLC19A1SLC46A1GART | |
| SCHEMBL9535837 | 0.86 | GART (0.63) | DHFRGART | |
| SCHEMBL9538587 | 0.84 | DHFR (0.61) | DHFRFOLR1SLC19A1SLC46A1GART | |
| SCHEMBL9446052 | 0.80 | GART (0.59) | DHFRFOLR1SLC19A1SLC46A1GART | |
| SCHEMBL9535831 | 0.80 | GART (0.72) | DHFRGART | |
| SCHEMBL9263780 | 0.78 | GART (0.67) | DHFRFOLR1SLC19A1SLC46A1GART | |
| SCHEMBL9208525 | 0.78 | GART (0.60) | DHFRFOLR1SLC19A1SLC46A1GART | |
| SCHEMBL9208538 | 0.78 | GART (0.60) | DHFRFOLR1SLC19A1SLC46A1GART | |
| SCHEMBL17790961 | 0.78 | DHFR (0.54) | DHFRGART | |
| SCHEMBL9054749 | 0.75 | DHFR (0.52) | DHFRFOLR1SLC19A1SLC46A1GART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215063-B1 | PYRIDO (2,3-d )PYRIMIDIN DERIVATIVES | UNIV PRINCETON (US) | 1993-11-03 | — | — | EP | claimed |