Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.75 |
| ▸ | HNF4A | P41235 | 2/20 | 0.73 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 4/20 | 0.55 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14156901 | 0.86 | CA12 (0.66) | ACMSDHNF4AALOX5XDHSLC22A12 | |
| SCHEMBL23143189 | 0.86 | ACMSD (1.00) | ACMSDHNF4AALOX5ESR1ESR2 | |
| SCHEMBL2536183 | 0.85 | ACMSD (1.00) | ACMSDHNF4AALOX5XDHSLC22A12 | |
| SCHEMBL29810721 | 0.85 | ACMSD (1.00) | ACMSDHNF4AALOX5XDHSLC22A12 | |
| SCHEMBL29441950 | 0.84 | ACMSD (0.83) | ACMSDHNF4AXDHSLC22A12ESR2 | |
| SCHEMBL2773864 | 0.84 | ACMSD (0.83) | ACMSDHNF4AXDHSLC22A12ESR2 | |
| SCHEMBL18735541 | 0.82 | ACMSD (0.88) | ACMSDHNF4AXDHSLC22A12ESR2 | |
| SCHEMBL569383 | 0.81 | ACMSD (0.68) | ACMSDHNF4AESR1ESR2MCL1 | |
| SCHEMBL30456738 | 0.81 | ACMSD (0.77) | ACMSDHNF4AXDHSLC22A12ESR2 | |
| SCHEMBL3294945 | 0.80 | ANO1 (0.60) | ACMSDHNF4AALOX5MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | claimed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | claimed |
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |