Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 4/20 | 1.00 |
| ▸ | HNF4A | P41235 | 2/20 | 1.00 |
| ▸ | DHFR | P00374 | 1/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.71 |
| ▸ | XDH | P47989 | 3/20 | 0.65 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.58 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.58 |
| ▸ | PPM1B | O75688 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29810721 | 1.00 | ACMSD (1.00) | ACMSDHNF4ADHFRMCL1XDH | |
| SCHEMBL18735541 | 0.94 | ACMSD (0.88) | ACMSDHNF4ADHFRMCL1XDH | |
| SCHEMBL2773864 | 0.91 | ACMSD (0.83) | ACMSDHNF4ADHFRMCL1XDH | |
| SCHEMBL29441950 | 0.91 | ACMSD (0.83) | ACMSDHNF4ADHFRMCL1XDH | |
| SCHEMBL9245988 | 0.88 | ACMSD (0.78) | ACMSDHNF4ADHFRMCL1XDH | |
| SCHEMBL22126663 | 0.88 | ACMSD (0.78) | ACMSDHNF4ADHFRMCL1XDH | |
| SCHEMBL30456738 | 0.87 | ACMSD (0.77) | ACMSDHNF4ADHFRMCL1XDH | |
| SCHEMBL22362635 | 0.86 | ACMSD (0.76) | ACMSDHNF4ADHFRMCL1XDH | |
| SCHEMBL31070130 | 0.86 | ACMSD (0.75) | ACMSDHNF4ADHFRMCL1XDH | |
| SCHEMBL28364476 | 0.86 | ACMSD (0.75) | ACMSDHNF4ADHFRMCL1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842696-B2 | Piperazine derivatives as inhibitors of stearoyl-CoA desaturase | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-30 | — | — | US | claimed |
| US-20090221583-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-03 | — | — | US | claimed |
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | claimed |
| US-20250162979-A1 | P-DIPHENYL COMPOUND DERIVATIVE MIXTURE AND METHOD OF PRODUCING THE SAME | HODOGAYA CHEMICAL CO., LTD. (JP) | 2025-05-22 | — | — | US | disclosed |
| US-20220324791-A1 | P-DIPHENYL COMPOUND DERIVATIVE MIXTURE AND METHOD OF PRODUCING THE SAME | HODOGAYA CHEMICAL CO., LTD. (JP) | 2022-10-13 | — | — | US | disclosed |
| CN-114096592-A | Metal organic framework with localized defects for gas separation | 埃克森美孚研究工程公司 | 2022-02-25 | — | — | CN | disclosed |
| US-20210139521-A1 | DIARYL TREHALOSE COMPOUNDS AND USES THEREOF | THE UNIV OF MONTANA (US) | 2021-05-13 | — | — | US | disclosed |
| CN-111356431-A | Self-reversible inverse latex comprising an alkyl polyglycoside as inverse, use thereof as thickener, and cosmetic composition comprising same | 化工产品开发公司SEPPIC | 2020-06-30 | — | — | CN | disclosed |
| CN-107674205-B | Thermosetting wholly aromatic polyester imide liquid crystal and preparation method thereof | 苏州大学 | 2020-06-16 | — | — | CN | disclosed |
| CN-106674051-A | Preparation method for 3-cyano-4-isopropoxy phenyl benzoate | 苏州山青竹生物医药有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-106674045-A | Preparation method of 3-cyano-4-isopropoxybenzoic acid | 苏州山青竹生物医药有限公司 | 2017-05-17 | — | — | CN | disclosed |
| US-7842696-B2 | Piperazine derivatives as inhibitors of stearoyl-CoA desaturase | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-30 | — | — | US | disclosed |
| CN-100548706-C | Thermal recording medium | OJI PAPER CO (JP) | 2009-10-14 | — | — | CN | disclosed |
| US-20090221583-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-03 | — | — | US | disclosed |
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |
| CN-101307174-A | Surface-mounting electronic component | UENO SEIYAKU KABUSHIKI KAISHA (JP) | 2008-11-19 | — | — | CN | disclosed |
| CN-101294002-A | Liquid crystalline polymer composition and molded article made of the same | UENO FINE CHEMICAL IND (JP) | 2008-10-29 | — | — | CN | disclosed |
| CN-101119855-A | Thermosensitive recording material | OJI PAPER CO (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-1193000-C | Biphenyl derivatives substituted by an aromatic or heteroaromatic radical and pharmaceutical and cometic compositions containing same | GALDERMA RES & DEV I (FR) | 2005-03-16 | — | — | CN | disclosed |
| CN-1236354-A | Aryl-or heteroaryl-substituted biphenyl derivatives and pharmaceutical and cosmetic compositions containing them | GALDERMA RES & DEV (FR) | 1999-11-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324791-A1 | P-DIPHENYL COMPOUND DERIVATIVE MIXTURE AND METHOD OF PRODUCING THE SAME | DDT, CYP2D6, CYP3A4 | ACMSD 692/4885HNF4A 620/4885DHFR 53/4885 |
| US-20250162979-A1 | P-DIPHENYL COMPOUND DERIVATIVE MIXTURE AND METHOD OF PRODUCING THE SAME | DDT, CYP2D6, CYP3A4 | ACMSD 692/4885HNF4A 620/4885DHFR 53/4885 |
| US-20090221583-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | ACMSD 1970/4885HNF4A 1844/4885DHFR 146/4885 |
| US-20210139521-A1 | DIARYL TREHALOSE COMPOUNDS AND USES THEREOF | TREH, STT3B, DDOST | ACMSD 931/4885HNF4A 3599/4885DHFR 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.