Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090985 | 0.86 | CA12 (0.65) | CA2CA12CA1CA7CA9 | |
| SCHEMBL2089116 | 0.86 | CA12 (0.65) | CA2CA12CA1CA7CA9 | |
| SCHEMBL27855901 | 0.86 | CA12 (0.46) | CA2CA12CA1CA7CA9 | |
| SCHEMBL2761677 | 0.86 | MAPK1 (0.46) | CA2CA12CA1CA7CA9 | |
| SCHEMBL27993733 | 0.84 | TNFSF11 (0.49) | CA2CA12CA1CA7CA9 | |
| SCHEMBL27872641 | 0.84 | CA12 (0.44) | CA2CA12CA1CA7CA9 | |
| SCHEMBL2333834 | 0.84 | TSHR (0.55) | ALDH1A1TSHRTUBB4ATUBBTUBA3C | |
| SCHEMBL14579646 | 0.84 | ALDH1A1 (0.43) | CA2CA12CA1CA7CA9 | |
| SCHEMBL14788121 | 0.84 | ALDH1A1 (0.47) | CA2CA12CA1CA7CA9 | |
| SCHEMBL2089135 | 0.82 | ALDH1A1 (0.43) | CA2CA12CA1CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928473-A1 | REGIOSELECTIVE N-2 ARYLATION OF INDAZOLES | Merck Sharp & Dohme Corp. (US) | 2015-10-14 | — | — | EP | claimed |
| WO-2014088983-A1 | REGIOSELECTIVE N-2 ARYLATION OF INDAZOLES | MERCK SHARP & DOHME CORP. (US) | 2014-06-12 | — | — | WO | claimed |
| EP-2097370-A2 | COMPOUNDS AND METHODS FOR AMINO-ALKYLENEDIOL SYNTHESIS | F. Hoffmann-Roche AG (CH) | 2009-09-09 | — | — | EP | claimed |
| WO-2008077799-A2 | COMPOUNDS AND METHODS FOR AMINO-ALKYLENEDIOL SYNTHESIS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-07-03 | — | — | WO | claimed |
| US-5356914-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1994-10-18 | — | — | US | claimed |
| EP-0552213-A1 | 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES | BEECHAM GROUP PLC (GB) | 1993-07-28 | — | — | EP | claimed |
| WO-1992006959-A1 | 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-04-30 | — | — | WO | claimed |
| CN-118326723-A | Color ink for spinning and preparation method thereof | 珠海华彩新材料科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-4396176-A1 | INDOLE COMPOUNDS AND USES THEREOF IN THE TREATEMENT OF CYSTIC FIBROSIS | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| EP-4396179-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2024137705-A1 | 2-HYDROXY AND 4-HYDROXY GLYCOLIPIDS AND THEIR DERIVATIVES | GlycoSurf, Inc. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024044657-A1 | BIOCATALYSTS AND METHODS THEREOF | TESARO, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| WO-2001029041-A1 | ALKYLAMINO SUBSTITUTED BICYCLIC NITROGEN HETEROCYCLES AS INHIBITORS OF P38 PROTEIN KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-26 | — | — | WO | disclosed |
| WO-2000034313-A1 | PROCOLLAGEN C-PROTEINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-15 | — | — | WO | disclosed |
| EP-0853497-A2 | MATRICES WITH MEMORIES, SENSORS WITH MEMORIES AND USES THEREOF | Irori (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997012680-A9 | MATRICES WITH MEMORIES, SENSORS WITH MEMORIES AND USES THEREOF | — | 1998-02-26 | — | — | WO | disclosed |
| WO-1997012680-A2 | MATRICES WITH MEMORIES, SENSORS WITH MEMORIES AND USES THEREOF | IRORI (US) | 1997-04-10 | — | — | WO | disclosed |
| US-5356914-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1994-10-18 | — | — | US | disclosed |
| WO-1992006959-A1 | 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | CA2 880/4885CA12 1230/4885CA1 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.