Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26940436 | 0.81 | CA2 (0.48) | CA2CA1MAPK1TDP1PTGES | |
| SCHEMBL448884 | 0.81 | CA2 (0.48) | CA2CA1MAPK1TDP1PTGES | |
| SCHEMBL5163491 | 0.81 | CA2 (0.39) | CA2CA1MAPK1FDPSTSHR | |
| SCHEMBL6517069 | 0.79 | CA2 (0.47) | CA2CA1MAPK1TDP1PTGES | |
| SCHEMBL5200419 | 0.79 | CA2 (0.42) | CA2CA1MAPK1TSHRCYP3A4 | |
| SCHEMBL28846728 | 0.79 | CA2 (0.38) | CA2CA1MAPK1FDPSTSHR | |
| SCHEMBL6522497 | 0.79 | CA2 (0.47) | CA2CA1MAPK1TDP1PTGES | |
| SCHEMBL6521204 | 0.79 | CA2 (0.47) | CA2CA1MAPK1TDP1PTGES | |
| SCHEMBL10728407 | 0.79 | CA2 (0.47) | CA2CA1MAPK1TDP1PTGES | |
| SCHEMBL6521659 | 0.79 | CA2 (0.47) | CA2CA1MAPK1TDP1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543936-A4 | RENIN INHIBITORS | — | 1993-06-30 | — | — | EP | disclosed |
| EP-0543936-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1993-06-02 | — | — | EP | disclosed |