Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | BID | P55957 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 4/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 2/20 | 0.34 |
| ▸ | F3 | P13726 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418567 | 0.80 | NPC1 (0.40) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL4564307 | 0.78 | GAA (0.41) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL4761870 | 0.72 | HCAR2 (0.44) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL30437790 | 0.71 | PPARA (0.39) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL3263072 | 0.70 | ALDH1A1 (0.42) | PPARAMAPTHSD17B10HPGDHCAR3 | |
| SCHEMBL6560660 | 0.69 | NPC1 (0.39) | MEN1KMT2ALMNAGAAHPGD | |
| SCHEMBL6278663 | 0.69 | HCAR2 (0.38) | THRATHRBMEN1KMT2AHCAR3 | |
| SCHEMBL11107777 | 0.67 | THRB (0.35) | PPARAPPARGTHRATHRBMAPT | |
| SCHEMBL286114 | 0.66 | MEN1 (0.40) | BIDMCL1BCL2L1BAK1SAE1 | |
| SCHEMBL5734668 | 0.65 | PPARA (0.33) | PPARAMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |