Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Ethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylamine SCHEMBL28837477 | 1.00 | — | — | |
| Ethylamine SCHEMBL9536323 | 1.00 | — | — | |
| Ethylamine SCHEMBL9393995 | 1.00 | — | — | |
| Ethylamine SCHEMBL9393989 | 1.00 | — | — | |
| Ethylamine SCHEMBL127386 | 1.00 | DNM1 (0.40) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Ethylamine SCHEMBL473818 | 1.00 | — | — | |
| Ethylamine SCHEMBL23910301 | 0.94 | — | — | |
| Ethylamine SCHEMBL21751927 | 0.94 | — | — | |
| Ethylamine SCHEMBL1331327 | 0.93 | — | — | |
| Ethylamine SCHEMBL854887 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550635-A1 | FUSED RING ANALOGS OF NITROGEN CONTAINING NONAROMATIC HETEROCYCLES. | PFIZER (US) | 1993-07-14 | — | — | EP | disclosed |