Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Ethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylamine SCHEMBL28837477 | 1.00 | — | — | |
| Ethylamine SCHEMBL9536323 | 1.00 | — | — | |
| Ethylamine SCHEMBL9393995 | 1.00 | — | — | |
| Ethylamine SCHEMBL9393989 | 1.00 | — | — | |
| Ethylamine SCHEMBL9536330 | 1.00 | DNM1 (0.40) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Ethylamine SCHEMBL473818 | 1.00 | — | — | |
| Ethylamine SCHEMBL23910301 | 0.94 | — | — | |
| Ethylamine SCHEMBL21751927 | 0.94 | — | — | |
| Ethylamine SCHEMBL1331327 | 0.93 | — | — | |
| Ethylamine SCHEMBL854887 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575293-B2 | Resin composition for optical material and optical material using the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2013-11-05 | — | — | US | disclosed |
| EP-2058346-B1 | RESIN COMPOSITION FOR OPTICAL MATERIAL AND OPTICAL MATERIAL USING THE SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20110218363-A1 | METHOD FOR PRODUCING ALKENYL MERCAPTAN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-08 | — | — | US | disclosed |
| US-20100004421-A1 | RESIN COMPOSITION FOR OPTICAL MATERIAL AND OPTICAL MATERIAL USING THE SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-2058346-A1 | RESIN COMPOSITION FOR OPTICAL MATERIAL AND OPTICAL MATERIAL USING THE SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-0614876-B1 | Method of producing aromatic carbonate | MITSUBISHI CHEM CORP (JP) | 1997-04-09 | — | — | EP | disclosed |
| EP-0736512-A1 | Method of producing aromatic carbonate | Mitsubishi Chemical Corporation (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5543547-A | REACTION OF AROMATIC HYDROXY COMPOUND, CARBON MONOXIDE, AND OXYGEN CATALYZED WITH PALLADIUM COMPOUND, CERIUM COMPOUND, QUATERNARY AMMONIUM OR PHOSPHONIUM SALT, AND A QUINONE DERIVATIVE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0614876-A1 | Method of producing aromatic carbonate | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0077542-B1 | PROCESS FOR PREPARING DIESTERS OF MALONIC ACID | UBE INDUSTRIES, LTD. (JP) | 1985-09-18 | — | — | EP | disclosed |
| US-4539423-A | FROM KETENE CARBON MONOXIDE AND ESTER OF NITROUS ACID; PLATINUM GROUP CATALYST | UBE INDUSTRIES LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0077542-A1 | Process for preparing diesters of malonic acid | UBE INDUSTRIES, LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| US-4147699-A | β-Lactam precursors of penicillin and cephalosporin antibiotics | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1979-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218363-A1 | METHOD FOR PRODUCING ALKENYL MERCAPTAN | TST, MPST, HACL2 | DNM1 4656/4885ALDH1A1 79/4885TSHR 2601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.