Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17582826 | 0.84 | MERTK (0.60) | TDP1ATMKAT2BMERTKMAPT | |
| SCHEMBL17582922 | 0.79 | MEN1 (0.43) | KAT2BMERTKMAPTVCAM1KMT2A | |
| SCHEMBL2506704 | 0.78 | MERTK (0.47) | TDP1ATMMERTKMAPTVCAM1 | |
| SCHEMBL30615510 | 0.77 | EPAS1 (0.56) | TDP1ATMKAT2BMAPTKMT2A | |
| SCHEMBL4940492 | 0.77 | EPAS1 (0.56) | TDP1ATMKAT2BMAPTKMT2A | |
| SCHEMBL9537323 | 0.76 | CASP6 (0.51) | TDP1ATMMAPTKMT2ARAB9A | |
| SCHEMBL9535914 | 0.76 | MAP2K1 (0.47) | MAP2K1RAB9AALDH1A1SMN1; SMN2SOS1 | |
| SCHEMBL9535377 | 0.75 | LMNA (0.49) | TDP1ATMMAPTKMT2ARAB9A | |
| SCHEMBL9539498 | 0.75 | AKR1C3 (0.53) | TDP1ATMMAPTKMT2ARAB9A | |
| SCHEMBL11901853 | 0.75 | TDP1 (0.59) | TDP1KAT2BMERTKMAPTVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| CN-88103277-A | Novel N-alkane sulfonyl aniline derivatives and preparation method thereof and the pharmaceutical composition that comprises this material | — | 1988-12-07 | — | — | CN | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |