Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 6/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.44 |
| ▸ | GSK3B | P49841 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536474 | 0.83 | CACNA1F (0.64) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL9241429 | 0.81 | ALDH1A1 (0.54) | MEN1KMT2APOLBKCNH2TOP2A | |
| SCHEMBL9535359 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2APOLBKCNH2TOP2A | |
| SCHEMBL9538275 | 0.78 | ALDH1A1 (0.67) | MEN1KMT2APOLBKCNH2TOP2A | |
| SCHEMBL9535715 | 0.76 | KCNH2 (0.63) | MEN1KMT2APOLBKCNH2GSK3B | |
| SCHEMBL9149448 | 0.76 | TOP2A (0.58) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL9535290 | 0.75 | DPP4 (0.62) | KMT2APOLBTOP2ATOP2BGSK3B | |
| SCHEMBL9145961 | 0.74 | MEN1 (0.46) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL9536591 | 0.72 | CACNA1F (0.61) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL9535816 | 0.72 | ALDH1A1 (0.45) | MEN1KMT2ATOP2ATOP2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013090-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES AND PROCESSES FOR PREPARING SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |