SCHEMBL9536476

SCHEMBL9536476

CC1(C)Cc2cn[c]nc2C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL207389 0.65
SCHEMBL9536542 0.64
SCHEMBL159386 0.64 CDK5 (0.33)
SCHEMBL558013 0.64
SCHEMBL9538304 0.63
SCHEMBL4148663 0.63 CDK5 (0.32)
SCHEMBL1482248 0.63
SCHEMBL24389273 0.60 ALDH1A1 (0.36) ALDH1A1HTT
SCHEMBL24388820 0.59 CYP11B2 (0.36) ALDH1A1HTT
SCHEMBL24388769 0.58 PLK1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0337944-B1 UREAS CIBA-GEIGY AG (CH) 1993-07-28 EP disclosed
US-4973690-A PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1990-11-27 US disclosed
EP-0337944-A1 Ureas CIBA-GEIGY AG (CH) 1989-10-18 EP disclosed