Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | NPR3 | P17342 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2593811 | 0.77 | CSF1R (0.41) | FPR2SCN9AKMT2ALMNAMAPT | |
| SCHEMBL16160098 | 0.77 | CSF1R (0.41) | FPR2SCN9AKMT2ALMNAMAPT | |
| SCHEMBL25867761 | 0.76 | TRPM8 (0.39) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9953290 | 0.72 | SCN9A (0.45) | FPR2SCN9AKMT2ALMNAMAPT | |
| SCHEMBL9953292 | 0.72 | SCN9A (0.45) | FPR2SCN9AKMT2ALMNAMAPT | |
| SCHEMBL14743767 | 0.71 | SCN9A (0.59) | FPR2SCN9ALMNACA12NPR3 | |
| SCHEMBL14743097 | 0.71 | SCN9A (0.59) | FPR2SCN9ALMNACA12NPR3 | |
| SCHEMBL22873621 | 0.68 | PTGDR (0.37) | NPSR1CA12CA1CA14 | |
| SCHEMBL8819479 | 0.68 | RXRA (0.38) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL26698986 | 0.67 | MAPT (0.38) | KMT2ALMNAMAPTALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005011-A1 | NOVEL IMMUNOSUPPRESSANTS | SANDOZ LTD. (CH) | 1993-03-18 | — | — | WO | disclosed |