Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 7/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535978 | 0.83 | MAPT (0.53) | HDAC1HDAC3NCOR2HDAC2HPGD | |
| SCHEMBL9537015 | 0.83 | MAPK14 (0.48) | HDAC1HDAC3NCOR2HDAC2HPGD | |
| SCHEMBL9536532 | 0.82 | KMT2A (0.52) | MEN1KMT2ANPC1RAB9AKCNK3 | |
| SCHEMBL9536986 | 0.80 | PTGS1 (0.48) | HDAC1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9535539 | 0.80 | MAPK14 (0.42) | HDAC1HDAC3NCOR2HDAC2HPGD | |
| SCHEMBL9536752 | 0.80 | ALDH1A1 (0.43) | HDAC1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9534376 | 0.79 | MAPK14 (0.46) | HDAC1HPGD | |
| SCHEMBL9535502 | 0.78 | MAPT (0.46) | HDAC1HDAC3NCOR2HDAC2POLB | |
| Diethylamine SCHEMBL9537391 | 0.77 | MAPK14 (0.41) | HDAC1HDAC3NCOR2HDAC2HPGD | |
| SCHEMBL9535727 | 0.75 | ALDH1A1 (0.40) | HDAC1KMT2AHDAC3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |