Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540198 | 0.84 | PTPN1 (0.58) | PTPN1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL4808309 | 0.81 | PTPN1 (0.61) | PTPN1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL2065774 | 0.81 | PTPN1 (0.61) | PTPN1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL4582840 | 0.79 | PTPN1 (0.63) | PTPN1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL16594594 | 0.79 | PTPN1 (0.56) | PTPN1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL951041 | 0.78 | PTPN1 (0.61) | PTPN1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL30791550 | 0.78 | PTPN1 (0.61) | PTPN1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL10592759 | 0.77 | PTPN1 (0.54) | PTPN1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL16618597 | 0.77 | ALDH1A1 (0.60) | PTPN1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL1829879 | 0.77 | TSHR (0.61) | PTPN1TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557307-A1 | PROCESS FOR PRODUCING 4,5,6,7-TETRAHYDRO-IMIDAZO-(4,5,LJK) (1,4)-BENZODIAZEPINE-2-(1H)-THIONES AND INTERMEDIATE PRODUCTS | Roche Diagnostics GmbH (DE) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992008706-A1 | PROCESS FOR PRODUCING 4,5,6,7-TETRAHYDRO-IMIDAZO-(4,5,LJK) (1,4)-BENZODIAZEPINE-2-(1H)-THIONES AND INTERMEDIATE PRODUCTS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-05-29 | — | — | WO | disclosed |