Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.59 |
| ▸ | RXRA | P19793 | 2/20 | 0.57 |
| ▸ | RARG | P13631 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532301 | 0.99 | PPARG (0.60) | PPARGRXRARARGFFAR1CYP3A4 | |
| SCHEMBL9536496 | 0.90 | PPARG (0.61) | PPARGRXRARARGFFAR1PPARA | |
| SCHEMBL9123909 | 0.86 | PPARG (0.61) | PPARGRXRARARGFFAR1CYP3A4 | |
| SCHEMBL2699229 | 0.86 | PPARG (0.63) | PPARGRXRARARGFFAR1PPARA | |
| SCHEMBL9121895 | 0.85 | PPARG (0.66) | PPARGRXRARARGFFAR1PPARA | |
| SCHEMBL9120637 | 0.84 | PPARG (0.63) | PPARGRXRARARGFFAR1PPARA | |
| SCHEMBL12515224 | 0.83 | FFAR1 (0.69) | PPARGRXRAFFAR1CYP3A4PPARA | |
| SCHEMBL9536665 | 0.83 | LTB4R (0.40) | PPARGRXRARARGFFAR1 | |
| SCHEMBL6966428 | 0.82 | PPARG (0.64) | PPARGRXRARARGFFAR1CYP3A4 | |
| SCHEMBL9532314 | 0.82 | LTB4R (0.41) | PPARGRXRARARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555251-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | claimed |
| WO-1992007838-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | claimed |