Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532314 | 0.99 | LTB4R (0.41) | LTB4RLTB4R2PPARGRARGRXRA | |
| SCHEMBL9536508 | 0.91 | ITGB3 (0.44) | LTB4RLTB4R2PPARGRARGRXRA | |
| SCHEMBL9123920 | 0.87 | LTB4R (0.46) | LTB4RLTB4R2PPARGRARGRXRA | |
| SCHEMBL9535011 | 0.87 | PPARG (0.42) | LTB4RLTB4R2PPARGRARGRXRA | |
| SCHEMBL9121904 | 0.85 | MAPT (0.43) | PPARGRARGRXRALTA4HHRH3 | |
| SCHEMBL9536662 | 0.83 | PPARG (0.59) | PPARGRARGRXRAFFAR1 | |
| SCHEMBL9532301 | 0.82 | PPARG (0.60) | PPARGRARGRXRAFFAR1 | |
| SCHEMBL10468305 | 0.81 | NPY5R (0.44) | PPARGRARGRXRALTA4HHRH3 | |
| SCHEMBL9325005 | 0.79 | PPARG (0.48) | PPARGRARGRXRAFFAR1LTA4H | |
| SCHEMBL9326656 | 0.77 | HRH3 (0.48) | PPARGFFAR1HRH3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555251-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | claimed |
| WO-1992007838-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | claimed |