Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9212105 | 0.99 | NPSR1 (0.48) | NPSR1TSHRALDH1A1POLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL9214108 | 0.97 | NPSR1 (0.51) | NPSR1TSHRALDH1A1POLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL9212494 | 0.96 | NPSR1 (0.53) | NPSR1TSHRALDH1A1POLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL9208625 | 0.96 | NPSR1 (0.53) | NPSR1TSHRALDH1A1POLBCYP1A2 | |
| SCHEMBL9207413 | 0.96 | NPSR1 (0.46) | NPSR1TSHRALDH1A1POLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL9210450 | 0.95 | NPSR1 (0.45) | NPSR1TSHRALDH1A1POLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL9205111 | 0.84 | LMNA (0.39) | NPSR1TSHRALDH1A1POLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL9212229 | 0.82 | TSHR (0.39) | NPSR1TSHRALDH1A1POLBCYP1A2 | |
| SCHEMBL9203542 | 0.82 | TSHR (0.39) | NPSR1TSHRALDH1A1POLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL9216303 | 0.81 | TSHR (0.39) | NPSR1TSHRALDH1A1POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536169-A1 | 3H,7H]THIAZOLO 3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-04-14 | — | — | EP | disclosed |