Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484385 | 0.72 | HTR2A (0.38) | CES2HTR2A | |
| SCHEMBL8736635 | 0.72 | EDNRB (0.42) | CES2HTR2A | |
| SCHEMBL252162 | 0.71 | HTR2A (0.52) | CES2HTR2A | |
| SCHEMBL9538108 | 0.70 | IDO1 (0.34) | — | |
| SCHEMBL4552155 | 0.64 | IDO1 (0.45) | HTR2A | |
| SCHEMBL9547888 | 0.63 | HTR2A (0.42) | HTR2A | |
| SCHEMBL6112245 | 0.63 | BCHE (0.39) | HTR2A | |
| SCHEMBL8546525 | 0.62 | KDM4E (0.37) | CES2 | |
| SCHEMBL4551141 | 0.62 | HTR2A (0.39) | CES2HTR2A | |
| SCHEMBL16859501 | 0.62 | HSD17B10 (0.55) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530198-A1 | HETEROCYCLIC COMPOUNDS AS ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991015491-A1 | HETEROCYCLIC COMPOUNDS AS ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1991-10-17 | — | — | WO | disclosed |