Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536703 | 0.70 | CES2 (0.32) | — | |
| SCHEMBL9533989 | 0.64 | CYP19A1 (0.52) | — | |
| SCHEMBL11422707 | 0.63 | NPC1 (0.46) | IDO1 | |
| SCHEMBL1240611 | 0.61 | HRAS (0.46) | IDO1 | |
| SCHEMBL8011663 | 0.61 | ACHE (0.51) | — | |
| SCHEMBL19853420 | 0.60 | ATM (0.52) | IDO1 | |
| SCHEMBL1829762 | 0.59 | NPC1 (0.50) | IDO1 | |
| SCHEMBL437919 | 0.59 | MAOA (0.48) | IDO1 | |
| SCHEMBL6112245 | 0.59 | BCHE (0.39) | — | |
| SCHEMBL16352091 | 0.58 | NPC1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530198-A1 | HETEROCYCLIC COMPOUNDS AS ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991015491-A1 | HETEROCYCLIC COMPOUNDS AS ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1991-10-17 | — | — | WO | disclosed |