SCHEMBL9536725

SCHEMBL9536725

CC(C(=O)O)n1cnc2c(Cl)ncnc21

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 7/20 0.45
FGFR4 P22455 7/20 0.45
FDPS P14324 1/20 0.45
P2RX7 Q99572 2/20 0.43
ADORA2A P29274 2/20 0.43
ADORA2B P29275 2/20 0.43
ADORA1 P30542 2/20 0.43
PI4KA P42356 1/20 0.43
PI4K2B Q8TCG2 1/20 0.43
PI4K2A Q9BTU6 1/20 0.43
PI4KB Q9UBF8 1/20 0.43
USP5 P45974 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CCNB2 O95067 4/20 0.40
CDK1 P06493 4/20 0.40
CCNB1 P14635 4/20 0.40
CCNB3 Q8WWL7 4/20 0.40
CDK2 P24941 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5281840 0.82 FDPS (0.45) FGFR1FGFR4FDPSP2RX7ADORA2A
SCHEMBL48132 0.82 ADORA2A (0.67) ADORA2AADORA2BADORA1PI4KAPI4K2B
SCHEMBL11258096 0.81 ADORA2A (0.47) FGFR1FGFR4FDPSP2RX7ADORA2A
SCHEMBL31331738 0.80 ADORA2A (0.64) FGFR1FGFR4FDPSADORA2AADORA2B
SCHEMBL2475932 0.80 ADORA2A (0.64) FGFR1FGFR4FDPSADORA2AADORA2B
SCHEMBL11596392 0.79 ADORA2A (0.49) FGFR1FGFR4FDPSP2RX7ADORA2A
SCHEMBL21539218 0.78 ADORA2A (0.51) FGFR1FGFR4FDPSP2RX7ADORA2A
SCHEMBL11596724 0.77 ADORA2A (0.50) FGFR1FGFR4FDPSP2RX7ADORA2A
SCHEMBL11596964 0.75 ADORA2A (0.45) FGFR1FGFR4FDPSP2RX7ADORA2A
SCHEMBL11595833 0.75 ADORA2A (0.45) FGFR1FGFR4FDPSP2RX7ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210077-A Plant growth regulators THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1993-05-11 US disclosed