Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 7/20 | 0.47 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.47 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | BLM | P54132 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222643 | 0.85 | NPSR1 (0.51) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL6205542 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRPMP22HPGD | |
| SCHEMBL1810243 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRPMP22HPGD | |
| SCHEMBL5433672 | 0.79 | HTR2C (0.49) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL23552891 | 0.79 | HTR2C (0.49) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL6716510 | 0.76 | NPSR1 (0.59) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL6716504 | 0.76 | NPSR1 (0.59) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL11387363 | 0.76 | NPSR1 (0.59) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL22166260 | 0.76 | HTR2C (0.53) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL24513290 | 0.74 | HTR1D (0.48) | NPSR1ALDH1A1LMNANFKB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522082-A4 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | — | 1993-06-09 | — | — | EP | disclosed |
| EP-0522082-A1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE. | GLASKY ALVIN J (US) | 1993-01-13 | — | — | EP | disclosed |