Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400976 | 0.99 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1NPY1RNPY2RHSD17B10 | |
| SCHEMBL9538333 | 0.98 | TP53 (0.36) | SMN1; SMN2L3MBTL1NPY1RNPY2RHSD17B10 | |
| SCHEMBL10400134 | 0.93 | NPY1R (0.36) | L3MBTL1NPY1RNPY2RACHETP53 | |
| SCHEMBL10400912 | 0.91 | NPY1R (0.35) | SMN1; SMN2L3MBTL1NPY1RNPY2RACHE | |
| SCHEMBL10400075 | 0.91 | SMN1; SMN2 (0.35) | SMN1; SMN2L3MBTL1NPY1RNPY2RHSD17B10 | |
| SCHEMBL10400076 | 0.89 | SMN1; SMN2 (0.33) | SMN1; SMN2L3MBTL1HSD17B10ACHETP53 | |
| SCHEMBL10400132 | 0.88 | MAPT (0.41) | HSD17B10ACHETP53LMNAPDE4B | |
| SCHEMBL9536988 | 0.85 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1HSD17B10ACHETP53 | |
| SCHEMBL10517472 | 0.85 | NPY1R (0.35) | SMN1; SMN2L3MBTL1NPY1RNPY2RACHE | |
| SCHEMBL10517367 | 0.84 | TP53 (0.39) | SMN1; SMN2L3MBTL1NPY1RNPY2RHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006477-A | — | — | None | — | — | JP | disclosed |
| EP-0337944-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| JP-H026477-A | N-PHENYL-N-PYRIMIDIN-2-YL UREA HAVING HERBICIDAL AND PLANT GROWTH REGULATING ACTIVITY | CIBA GEIGY AG | 1990-01-10 | — | — | JP | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |