Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401290 | 0.98 | TP53 (0.41) | TP53SMN1; SMN2L3MBTL1HSD17B10ACHE | |
| SCHEMBL10400778 | 0.94 | SMN1; SMN2 (0.40) | TP53SMN1; SMN2L3MBTL1HSD17B10ACHE | |
| SCHEMBL10400891 | 0.93 | ACHE (0.35) | TP53SMN1; SMN2ACHEBCHEGRIN1 | |
| SCHEMBL10400914 | 0.91 | TP53 (0.36) | TP53ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9538973 | 0.90 | SMN1; SMN2 (0.38) | TP53SMN1; SMN2L3MBTL1HSD17B10ACHE | |
| SCHEMBL10400078 | 0.88 | HSD17B10 (0.39) | TP53SMN1; SMN2L3MBTL1HSD17B10ACHE | |
| SCHEMBL10401010 | 0.88 | SMN1; SMN2 (0.38) | TP53SMN1; SMN2L3MBTL1HSD17B10KDM4E | |
| SCHEMBL9536789 | 0.88 | TP53 (0.37) | TP53SMN1; SMN2L3MBTL1HSD17B10ACHE | |
| SCHEMBL10400901 | 0.87 | MAPK14 (0.39) | TP53SMN1; SMN2HSD17B10MAPK14ALDH1A1 | |
| SCHEMBL10400944 | 0.86 | TSHR (0.37) | TP53SMN1; SMN2L3MBTL1HSD17B10ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |