Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.31 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536816 | 0.98 | SMN1; SMN2 (0.35) | TP53NPY1RNPY2RACHESMN1; SMN2 | |
| SCHEMBL10400976 | 0.97 | SMN1; SMN2 (0.37) | TP53NPY1RNPY2RACHESMN1; SMN2 | |
| SCHEMBL10400912 | 0.93 | NPY1R (0.35) | TP53NPY1RNPY2RACHESMN1; SMN2 | |
| SCHEMBL10400134 | 0.91 | NPY1R (0.36) | TP53NPY1RNPY2RACHEL3MBTL1 | |
| SCHEMBL10400076 | 0.91 | SMN1; SMN2 (0.33) | TP53ACHESMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL10400075 | 0.89 | SMN1; SMN2 (0.35) | NPY1RNPY2RACHESMN1; SMN2L3MBTL1 | |
| SCHEMBL10400132 | 0.88 | MAPT (0.41) | TP53ACHEHSD17B10LMNAALDH1A1 | |
| SCHEMBL9536239 | 0.85 | SMN1; SMN2 (0.35) | TP53ACHESMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL10401290 | 0.84 | TP53 (0.41) | TP53ACHESMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL9536988 | 0.83 | SMN1; SMN2 (0.37) | TP53ACHESMN1; SMN2L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337944-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |