Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA3 | P34903 | 11/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103073 | 0.87 | GABRA3 (0.59) | GABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL8097288 | 0.86 | GABRA3 (0.56) | GABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL8101152 | 0.80 | GABRA3 (0.60) | GABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL7328404 | 0.79 | GABRA5 (0.77) | GABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL8103365 | 0.76 | GABRA3 (0.62) | GABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL8100749 | 0.76 | GABRA3 (0.65) | GABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL8094937 | 0.75 | GABRA3 (0.61) | GABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL8094556 | 0.74 | GABRA3 (0.58) | GABRA3GABRA2GABRA1GABRA5 | |
| Hydrochloric Acid SCHEMBL8103212 | 0.74 | GABRA3 (0.61) | GABRA3GABRA2GABRA1GABRA5 | |
| SCHEMBL7327402 | 0.73 | GABRA5 (0.82) | GABRA3GABRA2GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547168-A1 | CERTAIN CYCLOALKYL IMIDAZOPYRIMIDINES, A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004351-A1 | CERTAIN CYCLOALKYL IMIDAZOPYRIMIDINES, A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |