Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533483 | 0.79 | PKM (0.36) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL11001844 | 0.78 | MEN1 (0.41) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL9538339 | 0.78 | KMT2A (0.62) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL12781970 | 0.78 | MEN1 (0.41) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL31073526 | 0.77 | KMT2A (0.56) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL3038360 | 0.77 | KMT2A (0.56) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL31073527 | 0.77 | KMT2A (0.56) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL9536228 | 0.77 | MEN1 (0.40) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL10495840 | 0.74 | MAPT (0.62) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL16798358 | 0.71 | CCNA2 (0.41) | MEN1KMT2ATP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102153556-B | Triazolopyrimidine compound and preparation method thereof | BEIJING YINGXIN TAIKANG INTERNAT TRADE CO LTD | 2013-03-27 | — | — | CN | disclosed |
| CN-102153556-A | Triazolopyrimidine compound and preparation method thereof | BEIJING YINGXIN TAIKANG INTERNAT TRADE CO LTD | 2011-08-17 | — | — | CN | disclosed |
| EP-0343752-B1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DOWELANCO (US) | 1993-12-01 | — | — | EP | disclosed |
| US-5163995-A | For use with grassy crops and soybeans | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| US-5010195-A | From 5-alkoxy-1,2,4-triazolo(1,5-c)pyrimidine | THE DOW CHEMICAL COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | disclosed |