Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537327 | 0.77 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL7201156 | 0.71 | TSHR (0.35) | ALDH1A1 | |
| SCHEMBL11571760 | 0.70 | TDP1 (0.39) | ALDH1A1 | |
| SCHEMBL5997983 | 0.67 | — | — | |
| SCHEMBL10602221 | 0.65 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8418758 | 0.65 | CYP11B1 (0.31) | — | |
| SCHEMBL353078 | 0.62 | — | — | |
| SCHEMBL10507737 | 0.61 | — | — | |
| SCHEMBL27901754 | 0.60 | — | — | |
| SCHEMBL1819835 | 0.60 | ALDH1A1 (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254595-A | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0375560-B1 | ARYLOXYPROPANOLAMINOTETRALINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ELF SANOFI (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0375560-A1 | Aryloxypropanolaminotetralines, process for their preparation and pharmaceutical compositions containing same | ELF SANOFI (FR) | 1990-06-27 | — | — | EP | disclosed |