Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602221 | 0.78 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL9537096 | 0.77 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL7201156 | 0.73 | TSHR (0.35) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL31454952 | 0.70 | MGLL (0.41) | — | |
| SCHEMBL10600807 | 0.69 | PDCD4 (0.34) | ALDH1A1 | |
| SCHEMBL8418758 | 0.67 | CYP11B1 (0.31) | — | |
| SCHEMBL8734914 | 0.62 | — | — | |
| SCHEMBL1819835 | 0.61 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL353078 | 0.60 | — | — | |
| Methyl Alcohol SCHEMBL28173966 | 0.59 | TSHR (0.45) | ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254595-A | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0375560-B1 | ARYLOXYPROPANOLAMINOTETRALINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ELF SANOFI (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0375560-A1 | Aryloxypropanolaminotetralines, process for their preparation and pharmaceutical compositions containing same | ELF SANOFI (FR) | 1990-06-27 | — | — | EP | disclosed |