Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | EDNRA | P25101 | 11/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | EDNRB | P24530 | 4/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535581 | 0.88 | KDM4E (0.60) | KDM4EEDNRAMAPTHTTEDNRB | |
| SCHEMBL9540898 | 0.85 | KDM4E (0.57) | KDM4EEDNRAMAPTHTTEDNRB | |
| SCHEMBL10761647 | 0.81 | KDM4E (0.64) | KDM4EEDNRAMAPTHTTEDNRB | |
| SCHEMBL9536999 | 0.80 | KDM4E (0.43) | KDM4EEDNRAMAPTHTTEDNRB | |
| SCHEMBL9146455 | 0.79 | MEN1 (0.58) | KDM4EEDNRAMAPTHTTEDNRB | |
| SCHEMBL10759304 | 0.77 | KDM4E (0.59) | KDM4EEDNRAMAPTHTTEDNRB | |
| SCHEMBL9144495 | 0.76 | KDM4E (0.58) | KDM4EEDNRAMAPTHTTEDNRB | |
| SCHEMBL9536517 | 0.76 | KDM4E (0.58) | KDM4EEDNRAMAPTHTTEDNRB | |
| SCHEMBL9536705 | 0.75 | KDM4E (0.57) | KDM4EEDNRAMAPTHTTEDNRB | |
| SCHEMBL9538849 | 0.75 | KDM4E (0.57) | KDM4EEDNRAMAPTHTTEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186367-B1 | ACIDIC INDOLE COMPOUNDS AND THEIR USE AS ANTIALLERGY AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |
| US-4675332-A | Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents | WARNER-LAMBERT COMPANY (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0186367-A2 | Acidic indole compounds and their use as antiallergy agents | WARNER-LAMBERT COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |