Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538105 | 0.87 | HDAC1 (0.51) | NPC1RAB9ASMN1; SMN2PLA2G7GAA | |
| SCHEMBL9538389 | 0.85 | BDKRB1 (0.49) | SMN1; SMN2PLA2G7MAPTLMNAKMT2A | |
| SCHEMBL9535652 | 0.81 | PTGS2 (0.54) | NPC1RAB9ASMN1; SMN2PLA2G7GAA | |
| SCHEMBL5674438 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9539158 | 0.77 | MAPT (0.43) | NPC1RAB9ASMN1; SMN2PLA2G7GAA | |
| SCHEMBL9539468 | 0.77 | CMA1 (0.48) | SMN1; SMN2PLA2G7GAAMAPTPOLB | |
| SCHEMBL9535456 | 0.76 | AKR1C3 (0.60) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL441676 | 0.76 | PTGS2 (0.55) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL29748830 | 0.76 | PTGS2 (0.55) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL9536230 | 0.76 | PTGS2 (0.55) | SMN1; SMN2PLA2G7MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |