Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535652 | 0.80 | PTGS2 (0.54) | CMA1MAPTALDH1A1SMN1; SMN2PLA2G7 | |
| SCHEMBL9534093 | 0.79 | ADRB3 (0.41) | PLA2G7CCR2PTGS2 | |
| SCHEMBL9538389 | 0.79 | BDKRB1 (0.49) | CMA1MAPTALDH1A1SMN1; SMN2PLA2G7 | |
| SCHEMBL5674438 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9537158 | 0.77 | NPC1 (0.50) | MAPTALDH1A1SMN1; SMN2PLA2G7GAA | |
| SCHEMBL441676 | 0.77 | PTGS2 (0.55) | CMA1MAPTALDH1A1SMN1; SMN2CCR2 | |
| SCHEMBL9536230 | 0.77 | PTGS2 (0.55) | CMA1MAPTALDH1A1SMN1; SMN2PLA2G7 | |
| SCHEMBL29748830 | 0.77 | PTGS2 (0.55) | CMA1MAPTALDH1A1SMN1; SMN2CCR2 | |
| SCHEMBL9539158 | 0.76 | MAPT (0.43) | CMA1MAPTALDH1A1SMN1; SMN2PLA2G7 | |
| SCHEMBL9538105 | 0.76 | HDAC1 (0.51) | MAPTALDH1A1SMN1; SMN2PLA2G7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |