Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.65 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | SHBG | P04278 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA4 | P22748 | 3/20 | 0.58 |
| ▸ | CA6 | P23280 | 3/20 | 0.58 |
| ▸ | CA5A | P35218 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.58 |
| ▸ | KDM1A | O60341 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537392 | 1.00 | ALOX5 (0.65) | ALOX5TTRSHBGCA12CA4 | |
| SCHEMBL9536412 | 0.92 | ALOX5 (0.74) | ALOX5TTRSHBGCA12CA4 | |
| SCHEMBL9536837 | 0.92 | ALOX5 (0.74) | ALOX5TTRSHBGCA12CA4 | |
| SCHEMBL9536416 | 0.92 | ALOX5 (0.74) | ALOX5TTRSHBGCA12CA4 | |
| SCHEMBL9579860 | 0.88 | ALOX5 (0.70) | ALOX5ALDH1A1PKMAKR1C3CYP2D6 | |
| SCHEMBL9579857 | 0.88 | ALOX5 (0.70) | ALOX5ALDH1A1PKMAKR1C3CYP2D6 | |
| SCHEMBL9695487 | 0.84 | ALOX5 (0.84) | ALOX5TTRCA12CA4CA6 | |
| SCHEMBL18509085 | 0.84 | ALOX5 (0.84) | ALOX5TTRCA12CA4CA6 | |
| SCHEMBL9536762 | 0.83 | ALOX5 (0.61) | ALOX5TTRKDM4EALDH1A1APP | |
| SCHEMBL9535267 | 0.83 | APP (0.53) | ALOX5TTRCA12CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241043-B1 | NOVEL DIARYLALKANOIDS HAVING ACTIVITY AS LIPOXYGENASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-09-01 | — | — | EP | claimed |