Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8330798 | 0.98 | SIGMAR1 (0.44) | SIGMAR1MC4RPNMTMEN1KMT2A | |
| SCHEMBL14272178 | 0.86 | PNMT (0.50) | PNMTMEN1KMT2A | |
| SCHEMBL30740655 | 0.82 | SIGMAR1 (0.50) | SIGMAR1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL9757228 | 0.81 | OPRL1 (0.46) | SIGMAR1MC4RPNMTCYP1A2ADRA2A | |
| SCHEMBL629986 | 0.80 | SIGMAR1 (0.46) | SIGMAR1MC4RPNMTCYP1A2ADRA2A | |
| SCHEMBL16693831 | 0.80 | SIGMAR1 (0.46) | SIGMAR1MC4RPNMTCYP1A2ADRA2A | |
| SCHEMBL4224502 | 0.80 | SIGMAR1 (0.46) | SIGMAR1MC4RPNMTCYP1A2ADRA2A | |
| SCHEMBL7595124 | 0.80 | MC4R (0.47) | SIGMAR1MC4RPNMTCYP1A2ADRA2A | |
| SCHEMBL6672942 | 0.80 | SIGMAR1 (0.62) | SIGMAR1MC4RCYP1A2ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL2490663 | 0.79 | SIGMAR1 (0.44) | SIGMAR1MC4RPNMTCYP1A2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005043-A1 | NOVEL ISATINOXIME DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 1993-03-18 | — | — | WO | disclosed |
| EP-0529636-A1 | Novel isatinoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-03-03 | — | — | EP | disclosed |