Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 4/20 | 0.43 |
| ▸ | GABRD | O14764 | 4/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.43 |
| ▸ | GABRE | P78334 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535854 | 0.88 | GABRA1 (0.57) | ALDH1A1MEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL9533356 | 0.87 | GABRA1 (0.51) | ALDH1A1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL9537497 | 0.86 | MEN1 (0.42) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL9535806 | 0.85 | GABRA1 (0.57) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9536032 | 0.85 | GABRA1 (0.47) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9538245 | 0.81 | GABRA1 (0.44) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL9534871 | 0.81 | MEN1 (0.48) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL9534774 | 0.80 | GABRA1 (0.53) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL9537349 | 0.79 | GABRA1 (0.74) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9535350 | 0.78 | GABRA1 (0.56) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234173-B1 | PHENOXY-SUBSTITUTED BETA-CARBOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-4945090-A | ANXIOLYTIC AGENTS, ANTICONVULSANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-07-31 | — | — | US | disclosed |
| EP-0234173-A2 | Phenoxy-substituted beta-carboline derivatives, their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-09-02 | — | — | EP | disclosed |