Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9538766 | 0.96 | HRH1 (0.47) | RAB9ASSTR5HRH1KCNH2CYP2D6 | |
| Oxalic Acid SCHEMBL9538773 | 0.96 | HRH1 (0.47) | RAB9ASSTR5HRH1KCNH2CYP2D6 | |
| SCHEMBL9536935 | 0.88 | NPSR1 (0.55) | RAB9ASSTR5HRH1KCNH2CYP2D6 | |
| SCHEMBL9537554 | 0.83 | HRH1 (0.63) | RAB9ASSTR5HRH1KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9537670 | 0.83 | RAB9A (0.55) | RAB9ASSTR5HRH1KCNH2CYP2D6 | |
| SCHEMBL9536663 | 0.83 | RAB9A (0.55) | RAB9ASSTR5HRH1KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9539517 | 0.82 | HRH1 (0.62) | RAB9ASSTR5HRH1KCNH2CYP2D6 | |
| SCHEMBL9536543 | 0.82 | SSTR5 (0.66) | RAB9ASSTR5HRH1KCNH2CYP2D6 | |
| SCHEMBL9537797 | 0.81 | RAB9A (0.57) | RAB9ASSTR5HRH1KCNH2CYP2D6 | |
| SCHEMBL9536904 | 0.81 | RAB9A (0.50) | RAB9ASSTR5HRH1KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | claimed |