SCHEMBL9537571

SCHEMBL9537571

OC1CNSc2ccsc21

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.30
HRH4 Q9H3N8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9058413 0.73 CYP3A4 (0.30)
SCHEMBL27344161 0.67 CHRNB4 (0.33)
SCHEMBL2839565 0.65 PNMT (0.42) HRH1HRH4
SCHEMBL9522336 0.65 MEN1 (0.31)
Hydrochloric Acid SCHEMBL11010216 0.64 PNMT (0.41) HRH1HRH4
SCHEMBL11834375 0.63 GID4 (0.32)
SCHEMBL7508842 0.62 CA1 (0.34) HRH1HRH4
SCHEMBL11833320 0.60
SCHEMBL2834973 0.59 GID4 (0.32)
Hydrochloric Acid SCHEMBL11008940 0.58 GID4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0527801-A4 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS 1993-03-10 EP disclosed
EP-0527801-A1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS ALCON LABORATORIES, INC. (US) 1993-02-24 EP disclosed
WO-1991015486-A1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS ALCON LABORATORIES, INC. (US) 1991-10-17 WO disclosed