Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
| ▸ | LCAT | P04180 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537856 | 0.93 | AKR1C3 (0.44) | AKR1C3PDE10AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3608739 | 0.86 | AKR1C3 (0.42) | AKR1C3PDE10AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL21588309 | 0.85 | MAP4K4 (0.48) | AKR1C3PDE10AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL14127793 | 0.80 | MAPT (0.57) | AKR1C3PDE10AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL21812435 | 0.79 | ADRA1A (0.47) | AKR1C3PDE10AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9541652 | 0.79 | HRH3 (0.42) | MAPTHRH3 | |
| SCHEMBL578538 | 0.79 | HRH3 (0.50) | AKR1C3ACACBHRH3 | |
| SCHEMBL1751227 | 0.79 | HRH3 (0.41) | AKR1C3PDE10AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1751229 | 0.79 | HRH3 (0.41) | AKR1C3PDE10AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL15205622 | 0.79 | HRH3 (0.41) | AKR1C3PDE10AGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006118-A1 | ANTIBACTERIAL, ANTIMYCOPLASMAL COMPOUNDS RELATED TO MUPIROCIN | SMITHKLINE BEECHAM PLC (GB) | 1993-04-01 | — | — | WO | disclosed |