Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538451 | 0.87 | MAPT (0.60) | MAPTLMNAMEN1POLBKMT2A | |
| SCHEMBL9541467 | 0.80 | MAPT (0.60) | MAPTLMNAMEN1POLBKMT2A | |
| SCHEMBL186009 | 0.71 | MEN1 (0.61) | MAPTLMNAMEN1POLBKMT2A | |
| SCHEMBL9533173 | 0.71 | MAOB (0.65) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL9379932 | 0.71 | MEN1 (0.64) | MAPTLMNAMEN1POLBKMT2A | |
| SCHEMBL2791070 | 0.71 | MAPT (0.69) | MAPTLMNAMEN1POLBKMT2A | |
| SCHEMBL12297633 | 0.69 | MAPT (0.58) | MAPTLMNAMEN1POLBKMT2A | |
| SCHEMBL32690204 | 0.69 | CYP1A2 (1.00) | MAPTLMNAMEN1POLBKMT2A | |
| SCHEMBL3529132 | 0.69 | CYP1A2 (0.55) | MAPTLMNAMEN1POLBKMT2A | |
| SCHEMBL9532937 | 0.68 | MAOB (0.62) | MAPTMEN1POLBKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003036-A1 | BENZOPYRANO[4,3-c]PYRAZOLES, THEIR PREPARATION AND THEIR USE AS IMMUNOMODULATORS | THE BOOTS COMPANY PLC (GB) | 1993-02-18 | — | — | WO | disclosed |