Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541467 | 0.88 | MAPT (0.60) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL9537650 | 0.87 | MAPT (0.54) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL186009 | 0.77 | MEN1 (0.61) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL9379932 | 0.76 | MEN1 (0.64) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL10382659 | 0.74 | MAOB (0.64) | MAPTMEN1KMT2APOLBGAA | |
| SCHEMBL32690204 | 0.73 | CYP1A2 (1.00) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL3529132 | 0.73 | CYP1A2 (0.55) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL12297633 | 0.73 | MAPT (0.58) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL9538966 | 0.73 | MEN1 (0.48) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL9536658 | 0.71 | MAOB (0.64) | MAPTMEN1KMT2AGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003036-A1 | BENZOPYRANO[4,3-c]PYRAZOLES, THEIR PREPARATION AND THEIR USE AS IMMUNOMODULATORS | THE BOOTS COMPANY PLC (GB) | 1993-02-18 | — | — | WO | disclosed |