Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379932 | 0.77 | MEN1 (0.64) | CYP1A2CYP2D6CYP2C9MAPTKMT2A | |
| SCHEMBL186009 | 0.74 | MEN1 (0.61) | CYP1A2CYP2D6CYP2C9MAPTKMT2A | |
| SCHEMBL6014889 | 0.74 | CA12 (0.71) | CYP1A2CYP2D6CYP2C9MAPTKMT2A | |
| SCHEMBL9541467 | 0.73 | MAPT (0.60) | CYP1A2CYP2D6CYP2C9MAPTKMT2A | |
| SCHEMBL9538451 | 0.73 | MAPT (0.60) | CYP1A2CYP2D6CYP2C9MAPTKMT2A | |
| SCHEMBL12297633 | 0.71 | MAPT (0.58) | CYP1A2CYP2D6CYP2C9MAPTKMT2A | |
| SCHEMBL3529132 | 0.71 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP2C9MAPTKMT2A | |
| SCHEMBL9537650 | 0.69 | MAPT (0.54) | CYP1A2CYP2D6CYP2C9MAPTKMT2A | |
| SCHEMBL18211847 | 0.68 | MAPT (0.62) | CYP1A2CYP2D6CYP2C9MAPTKMT2A | |
| SCHEMBL15233770 | 0.68 | MAPT (0.60) | CYP1A2CYP2D6CYP2C9MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260083724-A1 | COMPOUNDS TARGETING PAX3::FOXO1 FUSION PROTEIN | GEORGETOWN UNIVERSITY (US) | 2026-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260083724-A1 | COMPOUNDS TARGETING PAX3::FOXO1 FUSION PROTEIN | PAX3, FOXO1, PAXBP1 | CYP1A2 4450/4885CYP2D6 3236/4885CYP2C9 4570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.