Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060154 | 0.95 | CHRM3 (0.47) | CHRM3CHRM2CHRM1 | |
| SCHEMBL9311426 | 0.95 | CHRM3 (0.51) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL9059607 | 0.83 | CHRM3 (0.47) | CHRM3 | |
| SCHEMBL9059897 | 0.83 | ALDH1A1 (0.49) | CHRM3CHRM2CHRM1 | |
| SCHEMBL9059673 | 0.82 | CHRM3 (0.49) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL9059738 | 0.81 | CHRM3 (0.50) | CHRM3CHRM2CHRM1 | |
| SCHEMBL9059333 | 0.80 | CHRM3 (0.52) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL9059940 | 0.80 | CHRM3 (0.48) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL9536114 | 0.79 | CHRM3 (0.47) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL9059960 | 0.78 | MEN1 (0.38) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |